Diabetes 

Recruitment status:

Recruiting

Primary Sponsor:

Imperial College London

Recruitment countries:

United Kingdom

Health condition studied:

Diabetes

URL:

Link to the clinical trial website

About the trial

Interventions:

Key inclusion and exclusion criteria:

• 
  Inclusion Criteria:
  
  - Diagnosed with diabetes on the basis of fasting glucose and/or oral glucose tolerance
  test and/or HbA1c as per WHO criteria.
  
  - Diagnosed with diabetes between 6 months and 30 years of age.
  
  - South Asian ancestry- defined as self-reported ancestry and at least 2 grandparents
  from the Indian Subcontinent (India, Pakistan, Bangladesh or Sri Lanka).
  
  - European ancestry - defined as self-reported ancestry and at least 2 grandparents
  from within Europe.
  
  Exclusion Criteria:
  
  - An established secondary cause of diabetes exists (for example recurrent
  pancreatitis, pancreatectomy, new onset diabetes after transplantation, Cushing's
  syndrome, acromegaly, steroid induced).
  
  - Enrolled in another study.
  
  - Have active malignancy or under investigation for malignancy.
  

• Age minimum: 6 Months
• Age maximum: N/A
• Gender: Both

Primary outcomes:

Frequency of MODY

Secondary outcomes:

Comparison of biochemical and clinical characteristics in people with MODY between each ethnic group.
Comparison of clinical and biochemical characteristics of other subtypes of diabetes

Target sample size:

916

Study type:

Observational

Study design:

Time Perspective: Cross-Sectional

Contacts:

• Name: Nick S Oliver, MBBS, MRCP
• Address:
• Phone:
• Email:
• Affiliation: Imperial College London

• Name: Nick S Oliver, MRCP
• Address:
• Phone: +442033311065
• Email: nick.oliver@imperial.ac.uk
• Affiliation:

• Name: Shivani Misra, MBBS, MRCP
• Address:
• Phone:
• Email:
• Affiliation: Imperial College London

• Name: Shivani Misra, MBBS, MRCP
• Address:
• Phone: 0207 594 2460
• Email: s.misra@imperial.ac.uk
• Affiliation:

Technical details

Scientific title:

A Cross-sectional Study of Young-onset Diabetes in Two UK Ethnic Groups.

Sources of monetary support:

Please refer to primary and secondary sponsors

Secondary sponsors:

Main ID:

NCT02082132

Secondary ID:

13SM0659

Register:

ClinicalTrials.gov

Date of registration:

15/10/2024

Date of first enrollment:

October 2013

Last refreshed:

19 February 2025